CYP11A1 Recombinant Antibody,Bioss,bsm-60352m

Host

Mouse

Reactivity

Human

Application

WB, IHC-P, IHC-F, IF, ICC/IF

Conjugate

Unconjugated

Platform ID

BAB043888102

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameCYP11A1 Recombinant Antibody
Cat. No.bsm-60352m
Accession NumberP05108
Gene ID (Entrez)1583
HostMouse
IsotypeIgG1/Kappa
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IF, ICC/IF
Working DilutionsWB:=1:500-2000 | IHC-P:IHC-P=1:50-1:100 | IHC-F:ICC=1:50 | IF:IF=1:100-500 | ICC/IF:1:50-100
ClonalityRecombinant
Concentration1mg/ml
PurityPurified by Protein G.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]

Synonyms

Cholesterol 20 22 desmolase; Cholesterol desmolase; Cholesterol monooxygenase (side chain cleaving); Cholesterol side chain cleavage enzyme; Cholesterol side chain cleavage enzyme mitochondrial; Cholesterol side-chain cleavage enzyme; CP11A_HUMAN; CYP11A1; CYPXIA1; Cytochrome P450 11A1; Cytochrome P450 11A1 mitochondrial; Cytochrome P450 family 11 subfamily A polypeptide 1; Cytochrome P450 subfamily XIA; Cytochrome P450(scc); Cytochrome P450C11A1; mitochondrial; P450SCC; Steroid 20 22 lyase.

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