CYP1A2 antibody [6E2],Genetex,GTX84639

Host

Mouse

Reactivity

Human

Application

WB ICC/IF IHC-P FCM

Conjugate

Unconjugated

Platform ID

BAB509135022

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCYP1A2 antibody [6E2]
Cat. No.GTX84639
Gene ID (Entrez)1544
HostMouse
IsotypeIgG2a
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P FCM
ClonalityMonoclonal
Concentration0.8 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCYP1A2
ImmunogenFull length human recombinant protein of human CYP1A2 (NP_000752) produced in HEK293T cell.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.

Synonyms

cytochrome P450 family 1 subfamily A member 2 , CP12 , CYPIA2 , P3-450 , P450(PA)

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