CYP24A1 Rabbit mAb,ABclonal,A22615

Reactivity

Human

Application

IHC-P, IF/ICC, ELISA

Conjugate

Unconjugated

Platform ID

BAB978254794

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCYP24A1 Rabbit mAb
Cat. No.A22615
Accession NumberQ07973
Gene ID (Entrez)1591
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P, IF/ICC, ELISA
Working DilutionsIHC-P:1:100 - 1:500 | IF/ICC:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC58733
Molecular WeightRefer to figures
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

CP24; HCAI; CYP24; HCINF1; P450-CC24; CYP24A1

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