Cadherin Recombinant Antibody,Bioss,bsm-63043r-100ul

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IHC-F, IF(IHC-P)

Conjugate

Unconjugated

Platform ID

BAB827446986

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCadherin Recombinant Antibody
Cat. No.bsm-63043r-100ul
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IF(IHC-P)
Working DilutionsWB:1:500-2000 | IHC-P:IHC-P1:100-500 | IHC-F:IHC-F1:100-500 | IF(IHC-P):IFIHC-P1:100-500
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.

Synonyms

Cadherin;CDH3;CDHP;Cadherin-1;Cadherin-2;Cadherin-3;Cadherin-4;Cadherin-5;CAM 120/80;CD144;CD324;CD325;Cdh4;CDH5;CDHE;CDHN;E-cadherin;N-cadherin;NCAD;Neural cadherin;P-cadherin;Uvomorulin;Vascular endothelial cadherin

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