Caldesmon Antibody (YA6121),MedChemexpress,HY-P86429

Caldesmon Antibody (YA6121) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caldesmon.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,IHC-P,ICC/IF,IP,ELISA

Conjugate

Non-conjugated

Platform ID

BAB913212697

Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

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Tel: 609-228-6898
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Email:

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Product Specifications
Scientific Background
Synonyms

Specifications

NameCaldesmon Antibody (YA6121)
Cat. No.HY-P86429
Accession NumberQ05682
Gene ID (Entrez)800
HostRabbit
IsotypeIgG
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,IP,ELISA
Working DilutionsIHC-P: 1:200-1:1000; WB: 1:2000-1:10000; ICC/IF: 1:200-1:1000; ELISA: 1:5000-1:20000; IP: 1:50-1:200
ClonalityMonoclonal
Clone NumberYA6121
Molecular WeightPredicted band size: 93 kDa; Observed band size: 70 kDa
PurityProtein A
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

CALD1 is an actin- and myosin-binding protein implicated in regulating actomyosin interactions in smooth muscle and nonmuscle cells (potentially acting as a bridge between myosin and actin filaments). It stimulates tropomyosin binding to actin, thereby stabilizing actin filament structure. In muscle tissues, CALD1 inhibits actomyosin ATPase activity by binding to F-actin, with this inhibition attenuated by calcium-calmodulin and enhanced by tropomyosin. It interacts with actin, myosin, two tropomyosin molecules, and calmodulin. Additionally, CALD1 plays essential roles in cellular mitosis, receptor capping, and Schwann cell migration during peripheral nerve regeneration (by similar).

Synonyms

CALD1; CAD; CDM; Caldesmon; CDM

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