Caldesmon antibody [HL5575],Genetex,GTX646257

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB725176330

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCaldesmon antibody [HL5575]
Cat. No.GTX646257
Gene ID (Entrez)800
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB
ClonalityMonoclonal
Concentrationbatch dependent (Please refer to the vial label for the specific concentration.)
TargetCALD1
ImmunogenRecombinant fragment of human Caldesmon.
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Synonyms

caldesmon 1 , CDM , H-CAD , HCAD , L-CAD , LCAD , NAG22

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