Calmodulin antibody [2D1],Genetex,GTX22860

Host

Mouse

Reactivity

Human, Mouse, Rat, Bovine, Chicken, Fungi, Shrew, Bacteria

Application

WB ICC/IF IHC-P IHC-Fr FCM ELISA IHC Neutralizing /Inhibition

Conjugate

Unconjugated

Platform ID

BAB426386025

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCalmodulin antibody [2D1]
Cat. No.GTX22860
Gene ID (Entrez)326597
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Rat, Bovine, Chicken, Fungi, Shrew, Bacteria
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P IHC-Fr FCM ELISA IHC Neutralizing /Inhibition
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCALM
ImmunogenCalmodulin purified from Dictyostelium discoideum.
PurityProtein A purified
Appearance/FormLiquid
FormulationPBS,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Calmodulin is a small, highly conserved calcium binding protein found in all eukaryotic cells. With the capacity to bind up to four calcium ions, this 17 kDa protein acts as an important intracellular receptor for regulatory calcium signals. As it binds calcium, calmodulin undergoes conformational changes which can increase its affinity for target proteins. It acts both directly, through interaction with key target enzymes, and indirectly, via specific kinases. Studies have found that calmodulin participates in the regulation of several biological processes including energy and biosynthetic metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of both cAMP and calcium concentrations.

Synonyms

calmodulin-like , CALM2

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