Cardiac Troponin I antibody [P420],Genetex,GTX38780

Host

Mouse

Reactivity

Human

Application

ELISA Sandwich ELISA

Conjugate

Unconjugated

Platform ID

BAB397488638

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCardiac Troponin I antibody [P420]
Cat. No.GTX38780
Gene ID (Entrez)7137
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA Sandwich ELISA
ClonalityMonoclonal
Concentration5.57 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTNNI3
ImmunogenHighly purified human cardiac troponin I subunit.
PurityProtein A purified
Appearance/FormLiquid
Formulation10mM Sodium Phosphate, 0.85% NaCl,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]

Synonyms

troponin I3, cardiac type , CMD1FF , CMD2A , CMH7 , RCM1 , TNNC1 , cTnI

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