Caspase-1 Rabbit pAb- ABclonal,ABclonal,A20470
Reactivity
Mouse
Application
WB, ELISA
Conjugate
Unconjugated
Platform ID
BAB338837953
ABclonal
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Product Specifications
Scientific Background
Specifications
NameCaspase-1 Rabbit pAb- ABclonal
Cat. No.A20470
RRID#N/A
IsotypeIgG
ReactivityMouse
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:500 - 1:1000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight48kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only
Scientific Background
Enables cysteine-type endopeptidase activity. Involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of interleukin-1 beta production; and protein autoprocessing. Acts upstream of or within several processes, including membrane hyperpolarization; mitochondrial depolarization; and positive regulation of interleukin-1 alpha production. Located in extracellular region. Part of IPAF inflammasome complex. Is expressed in knee joint and metanephros. Orthologous to human CASP1 (caspase 1).
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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