Caspase-3 Mouse mAb,ABclonal,A17900
Reactivity
Human, Mouse
Application
WB, ELISA
Platform ID
BAB587763469
ABclonal
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Product Specifications
Scientific Background
Specifications
NameCaspase-3 Mouse mAb
Cat. No.A17900
RRID#N/A
IsotypeIgG1,Kappa
ReactivityHuman, Mouse
ApplicationWB, ELISA
Working DilutionsWB:1:500 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberAMC0214
Molecular Weight32kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only
Scientific Background
The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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