Caspase 3 antibody,Genetex,GTX73090

Host

Rabbit

Reactivity

Human, Mouse, Rat, Rabbit

Application

WB IHC-P IP IHC

Conjugate

Unconjugated

Platform ID

BAB298802237

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCaspase 3 antibody
Cat. No.GTX73090
Gene ID (Entrez)836
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Rabbit
ConjugationUnconjugated
ApplicationWB IHC-P IP IHC
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCASP3
ImmunogenRecombinant full length human caspase 3 protein.
PurityProtein A affinity purified
Appearance/FormLiquid
FormulationPBS, 0.2% BSA,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]

Synonyms

caspase 3 , CPP32 , CPP32B , SCA-1

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