Caspase 3 antibody [HL1314],Genetex,GTX636732

Host

Rabbit

Reactivity

Human

Application

ICC/IF

Conjugate

Unconjugated

Platform ID

BAB273014621

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCaspase 3 antibody [HL1314]
Cat. No.GTX636732
Gene ID (Entrez)836
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationICC/IF
ClonalityMonoclonal
Concentration1 mg/ml
TargetCASP3
ImmunogenThe immunogen used to generate this antibody corresponds to human Caspase 3.
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]

Synonyms

caspase 3 , CPP32 , CPP32B , SCA-1

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