Caspase 3 precursor Polyclonal Antibody,Bioss,bs-2593R

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, ELISA

Conjugate

Unconjugated

Platform ID

BAB678107439

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCaspase 3 precursor Polyclonal Antibody
Cat. No.bs-2593R
Accession NumberP55213
Gene ID (Entrez)25402
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, ELISA
Working DilutionsWB:1:300-5000 | ELISA:1:500-1000
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity).

Synonyms

Lice; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; IRP; Protein Yama; SREBP cleavage activity 1; SCA-1; Casp3; Cpp32

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