Caspase 4 antibody,Genetex,GTX113639

Host

Rabbit

Reactivity

Human, Dog, Pig

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB318826414

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCaspase 4 antibody
Cat. No.GTX113639
Gene ID (Entrez)837
HostRabbit
IsotypeIgG
ReactivityHuman, Dog, Pig
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityPolyclonal
Concentration0.89 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCASP4
ImmunogenRecombinant protein encompassing a sequence within the center region of human Caspase 4. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
Formulation0.1M Tris, 0.1M Glycine, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq]

Synonyms

caspase 4 , ICE(rel)II , ICEREL-II , ICH-2 , Mih1 , Mih1/TX , TX

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