Cell-Vive™ GMP Ultra-LEAF™ Biotin anti-HU CD133 RecAb SF, CD133, S16016B.Rec,BioLegend,394021

Host

Mouse

Application

FC - Quality tested

Platform ID

BAB155203611

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameCell-Vive™ GMP Ultra-LEAF™ Biotin anti-HU CD133 RecAb SF, CD133, S16016B.Rec
Cat. No.394021
HostMouse
IsotypeMouse IgG2a, κ
ApplicationFC - Quality tested
ClonalityRecombinant
Clone NumberS16016B.Rec
Concentration1 mg/mL
TargetCD133
PurityGMP Ultra-LEAF™ (Low Endotoxin, Azide-Free) Recombinant Serum Free antibody purified by affinity chromatography
Formulation0.1 µm filtered in phosphate-buffered solution, pH 7.2, with a final concentration of HPCD at 5%. Endotoxin level is < 0.01 EU/µg of the protein (< 0.001 ng/µg of the protein) as determined by the LAL test.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only

Scientific Background

CD133, also known as Prominin-1 and AC133 antigen, is a 120 kD pentaspan glycoprotein with 5 transmembrane domains. CD133 was initially described as a surface antigen specific for human hematopoietic stem cells and as a marker for murine neuroepithelial cells and some embryonic epithelia. Later on, CD133 was found on other stem cells, including endothelial progenitor cells, glioblastomas, neuronal, and glial stem cells. In addition to stem cells for normal tissue, CD133 was found on cancer cells, such as some leukemia cells and brain tumor cells. Although the biological function of CD133 is not completely understood, CD133 has been extensively used as a stem cell marker for normal and cancerous tissues.

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