Cell-Vive™ GMP Ultra-LEAF™ Biotin anti-HU CD3 RecAb SF, CD3, OKT3.Rec,BioLegend,317370

The OKT3.Rec recombinant antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex.Clone OKT3.Rec can block the binding of clones SK7 and UCHT1. The OKT3.Rec antibody is able to induce T cell activation.This GMP Ultra-LEAF™ Purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.1 µm filtered) is recommended for highly sensitive assays.

Host

Mouse

Application

FC - Quality tested

Platform ID

BAB092622400

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameCell-Vive™ GMP Ultra-LEAF™ Biotin anti-HU CD3 RecAb SF, CD3, OKT3.Rec
Cat. No.317370
HostMouse
IsotypeMouse IgG2a, κ
ApplicationFC - Quality tested
ClonalityRecombinant
Clone NumberOKT3.Rec
Concentration1.0 mg/mL
TargetCD3
PurityGMP Ultra-LEAF™ (Low Endotoxin, Azide-Free) Recombinant Serum Free antibody purified by affinity chromatography
Formulation0.1 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/µg of the protein (< 0.001 ng/µg of the protein) as determined by the LAL test.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only

Scientific Background

CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.

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