Cell-Vive™ GMP Ultra-LEAF™ Biotin anti-HU NKp46 RecAb SF, NKp46, 9E2.RecH1,BioLegend,331959

Host

Human

Application

FC - Quality tested

Platform ID

BAB466310530

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameCell-Vive™ GMP Ultra-LEAF™ Biotin anti-HU NKp46 RecAb SF, NKp46, 9E2.RecH1
Cat. No.331959
HostHuman
IsotypeHuman IgG1, κ
ApplicationFC - Quality tested
ClonalityRecombinant
Clone Number9E2.RecH1
Concentration1 mg/mL
TargetNKp46
PurityGMP Ultra-LEAF™ (Low Endotoxin, Azide-Free) Recombinant Serum Free antibody purified by affinity chromatography
Formulation0.1 µm filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/µg of the protein (< 0.001 ng/µg of the protein) as determined by the LAL test.
StorageThe antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF™ solution contains no preservative; handle under aseptic conditions.
Regulatory StatusResearch Use Only

Scientific Background

CD335, also known as NKp46, is a member of the natural cytotoxicity receptor (NCR) family which triggers cytotoxicity in NK cells. CD335 is directly involved in target cell recognition and lysis, and is exclusively expressed on CD3-CD56+NK cells, suggesting it is a universal marker for NK cells. NKp46, along with NKp30 and NKp44, is referred to as a natural cytoxicity receptor (NCR) and plays a very important role in killing virus-infected tumor cells and MHC-class I-unprotected cells.

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