Claudin-4 Rabbit mAb,ABclonal,A23841

Reactivity

Human

Application

WB, IP, ELISA

Conjugate

Unconjugated

Platform ID

BAB664649075

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

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Product Specifications
Scientific Background
Synonyms

Specifications

NameClaudin-4 Rabbit mAb
Cat. No.A23841
Accession NumberO14493
Gene ID (Entrez)1364
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IP, ELISA
Working DilutionsWB:1:7000 - 1:28000 | IP:0.5μg-4μg antibody for 400μg-600μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC61052
Molecular Weight18kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

Synonyms

CLDN4; CPE-R; CPER; CPETR; CPETR1; WBSCR8; hCPE-R; claudin-4; Claudin-4

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