Cleaved-PARP1 Antibody (YA498),MedChemexpress,HY-P80625

Cleaved-PARP1 Antibody (YA498) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cleaved-PARP1.

Host

Rabbit

Reactivity

Human

Application

WB

Conjugate

Non-conjugated

Platform ID

BAB249718683

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

MedChemexpress

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Email:

[email protected]

Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameCleaved-PARP1 Antibody (YA498)
Cat. No.HY-P80625
Accession NumberP09874
Gene ID (Entrez)142
HostRabbit
RRIDAB_3102149
IsotypeIgG
SensitivityEndogenous
ReactivityHuman
ConjugationNon-conjugated
ApplicationWB
Working DilutionsWB: 1:500-1:1000
ClonalityRecombinant,Monoclonal
Clone NumberYA498
Molecular WeightPredicted band size: 113 kDa; Observed band size: 89 kDa
ImmunogenSynthetic peptide corresponding to Human Cleaved PARP1.The exact sequence is proprietary to MCE.
Purityaffinity purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol and 0.05% BSA. Preservative: 0.01% Sodium azide
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

Cleaved-PARP1: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

Synonyms

PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1

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