Connexin 43 (phospho Ser368) antibody,Genetex,GTX79102

Host

Rabbit

Reactivity

Human

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB306698445

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameConnexin 43 (phospho Ser368) antibody
Cat. No.GTX79102
Gene ID (Entrez)2697
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetGJA1
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Connexin43 around the phosphorylation site of serine 367 (R-A-Sp-S-R).
PurityPurified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.From serum
Appearance/FormLiquid
FormulationPBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format),0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014]

Synonyms

AVSD3,CMDR,CX43,EKVP,GJA1,GJAL,HLHS1,HSS,ODDD,PPKCA,gap junction protein alpha 1,Connexin 43

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