Cripto Recombinant Antibody,Bioss,bsm-62062r-100ul

Host

Rabbit

Reactivity

Human

Application

WB, FCM, IF(ICC), IP

Conjugate

Unconjugated

Platform ID

BAB688091380

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameCripto Recombinant Antibody
Cat. No.bsm-62062r-100ul
Accession NumberP13385
Gene ID (Entrez)6997
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, FCM, IF(ICC), IP
Working DilutionsWB:1:500-2000 | FCM:FCM1:50-100 | IF(ICC):IFICC1:50-200 | IP:IP1:20-50
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.

Synonyms

CRGF; Cripto 1; cripto; Cripto1 growth factor; TDGF1.

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