Cripto1/CRIPTO Antibody (YA2245),MedChemexpress,HY-P82500
Cripto1/CRIPTO Antibody (YA2245) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cripto1/CRIPTO.
Host
Rabbit
Reactivity
Human
Application
WB,ICC/IF,IP,FC
Conjugate
Non-conjugated
Platform ID
BAB951605524
Suppliers
(1)Biomedical Life sciences
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Product Specifications
Verification Image
Scientific Background
Synonyms
Specifications
NameCripto1/CRIPTO Antibody (YA2245)
Cat. No.HY-P82500
Accession NumberP13385
Gene ID (Entrez)6997
HostRabbit
RRIDAB_3104607
IsotypeIgG
SensitivityEndogenous
ReactivityHuman
ConjugationNon-conjugated
ApplicationWB,ICC/IF,IP,FC
Working DilutionsWB: 1:500-1:1000; ICC/IF: 1:50-1:200; IP: 1:50; FC: 1:50-1:100
ClonalityRecombinant,Monoclonal
Clone NumberYA2245
Molecular WeightPredicted band size: 21 kDa; Observed band size: 21 kDa
ImmunogenA synthesized peptide derived from human Cripto1 aa20-88.
PurityAffinity Chromatography
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only
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Scientific Background
Cripto is a GPI-anchored cell membrane protein involved in the Nodal signaling pathway. Cell-associated CRIPTO functions as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by enabling soluble CRIPTO to act as a Nodal coreceptor on other cells (by similar: PubMed:27881714). It may also play a role in determining epiblastic cells that subsequently give rise to the mesoderm (by similar: PubMed:11909953).
Synonyms
CRGF; Cripto 1; cripto; Cripto1 growth factor; TDGF1
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