CrkL antibody [5E12],Genetex,GTX60462

Host

Mouse

Reactivity

Human, Mouse

Application

WB FCM ELISA

Conjugate

Unconjugated

Platform ID

BAB765668149

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCrkL antibody [5E12]
Cat. No.GTX60462
Gene ID (Entrez)1399
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB FCM ELISA
ClonalityMonoclonal
TargetCRKL
ImmunogenPurified recombinant fragment of human CRKL expressed in E. Coli.
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.03% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]

Synonyms

CRK like proto-oncogene, adaptor protein

Category Paths

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