CrkL antibody [GT466],Genetex,GTX634534

Host

Mouse

Reactivity

Human

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB583721732

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCrkL antibody [GT466]
Cat. No.GTX634534
Gene ID (Entrez)1399
HostMouse
IsotypeIgG2b
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetCRKL
ImmunogenRecombinant protein encompassing a sequence within the center region of human CrkL. The exact sequence is proprietary.
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]

Synonyms

CRK like proto-oncogene, adaptor protein

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