Cryptochrome 2 (CRY2) Antibody,Abbexa,abx005245

CRY2 Antibody is a Rabbit Polyclonal antibody against CRY2. This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB026568145

Abbexa

Headquarters

181 Cambridge Science Park Cambridge, CB4 0GJ United Kingdom

Contact

Tel: +44 (0) 1223 755950
Fax: +44 (0) 1223 755951

Product Specifications

Specifications

NameCryptochrome 2 (CRY2) Antibody
Cat. No.abx005245
Accession NumberQ49AN0
Gene ID (Entrez)1408
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB
Working DilutionsWB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Concentration1 mg/ml
Molecular WeightCalculated MW: 60 kDa/66 kDa Observed MW: 70 kDa
TargetCRY2
ImmunogenRecombinant fusion protein corresponding to human CRY2
PurityPurified by affinity chromatography.
Appearance/FormLiquid
FormulationPBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only

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