Ctip2 Antibody (YA4479)(PBS only),MedChemexpress,HY-P84782A

Ctip2 Antibody (YA4479) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Ctip2.

Host

Mouse

Reactivity

Human

Application

IHC-P,ICC/IF,FC,ELISA

Conjugate

Non-conjugated

Platform ID

BAB952993593

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

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MedChemexpress

Contact

Tel: 609-228-6898
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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCtip2 Antibody (YA4479)(PBS only)
Cat. No.HY-P84782A
Accession NumberQ9C0K0
Gene ID (Entrez)64919
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationNon-conjugated
ApplicationIHC-P,ICC/IF,FC,ELISA
Working DilutionsIHC-P: 1:200-1:1000; ICC/IF: 1:50-1:250; FC: 1:200-1:400; ELISA: 1:10000
Clone NumberYA4479
Molecular WeightPredicted band size: 96 kDa; Observed band size: 140 kDa
ImmunogenPurified recombinant fragment of human BCL11B (AA: 1-150) expressed in E. Coli.
Purityaffinity purified.
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS, pH 7.4.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

BCL11B is a key regulator of T-lymphocyte differentiation and survival during thymocyte development in mammals. It controls hematopoietic stem cell responsiveness to chemotactic signals by modulating CCR7 and CCR9 receptor expression, directing progenitor cell migration from bone marrow to thymus. Additionally, BCL11B regulates the IL2 promoter and enhances IL2 expression in activated CD4(+) T-lymphocytes. As a tumor suppressor, it represses transcription through direct, TFCOUP2-independent binding to GC-rich response elements (by similarity). It may also function in the P53-signaling pathway (by similarity).

Synonyms

ATL1; RIT1; CTIP2; IMD49; CTIP-2; ZNF856B; ATL1-beta; ATL1-alpha; ATL1-delta; ATL1-gamma; hRIT1-alpha

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