Cyclin Dependent Kinase Inhibitor 1C (CDKN1C) Antibody,Abbexa,abx001677

CDKN1C Antibody is a Rabbit Polyclonal antibody against CDKN1C. This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.