Cyclin E antibody,Genetex,GTX22094
Host
Rabbit
Reactivity
Human
Application
WB IP ELISA
Conjugate
Unconjugated
Platform ID
BAB300124131
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Product Specifications
Scientific Background
Synonyms
Specifications
NameCyclin E antibody
Cat. No.GTX22094
Gene ID (Entrez)898
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IP ELISA
ClonalityPolyclonal
TargetCCNE1
ImmunogenA KLH conjugated peptide corresponding to a region near the carboxy terminus of human Cyclin E.
PurityUnpurified
Appearance/FormLiquid
FormulationFiltered-steriled serum,0.01% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only
Scientific Background
Cyclin E is a regulatory subunit of cdk 2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
Synonyms
cyclin E1 , CCNE , pCCNE1
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.