Cyclooxygenase 1 Recombinant Antibody,Bioss,bsm-61288r-TR

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IHC-F, IF(IHC-P), IP

Conjugate

Unconjugated

Platform ID

BAB427371528

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCyclooxygenase 1 Recombinant Antibody
Cat. No.bsm-61288r-TR
Accession NumberP23219
Gene ID (Entrez)5742
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IF(IHC-P), IP
Working DilutionsWB:1:500-2000 | IHC-P:IHC-P1:50-200 | IHC-F:IHC-F1:50-200 | IF(IHC-P):IFIHC-P1:50-200 | IP:IP1:20-50
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Dual cyclooxygenase and peroxidase that plays an important role in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate, AA, C20:4(n-6)), with a particular role in the inflammatory response. The cyclooxygenase activity oxygenates AA to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide prostaglandin H2 (PGH2), the precursor of all 2-series prostaglandins and thromboxanes.

Synonyms

COX-1; COX1; COX3; Cyclooxygenase-1; PCOX1; PGG/HS; PGH synthase 1; PGH1; PGHS1; PHS1; Prostaglandin G/H synthase 1; Prostaglandin H2 synthase 1; PTGHS; PTGS1.

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