Cytochrome C Monoclonal Antibody, AbBy Fluor-555 Conjugated,Bioss,bsm-33193m-bf555-100ul

Host

Mouse

Reactivity

Human, Rat, Rabbit

Application

WB, IF

Conjugate

AbBy Fluor-555

Platform ID

BAB449372227

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameCytochrome C Monoclonal Antibody, AbBy Fluor-555 Conjugated
Cat. No.bsm-33193m-bf555-100ul
Accession NumberP99999
Gene ID (Entrez)54205
HostMouse
IsotypeIgG
ReactivityHuman, Rat, Rabbit
ConjugationAbBy Fluor-555
ApplicationWB, IF
Working DilutionsWB:1:300-5000 | IF:
ClonalityMonoclonal
Concentration1ug/ul
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

Synonyms

Cytochrome c; CYCS

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