Cytokeratin 18 antibody [5E8],Genetex,GTX84255

Host

Mouse

Reactivity

Human, Dog, Monkey

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB258010562

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameCytokeratin 18 antibody [5E8]
Cat. No.GTX84255
Gene ID (Entrez)3875
HostMouse
IsotypeIgG2b
ReactivityHuman, Dog, Monkey
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityMonoclonal
Concentration0.26 mg/ml (Please refer to the vial label for the specific concentration.)
TargetKRT18
ImmunogenHuman recombinant protein fragment corresponding to amino acids 69-372 of human CK18 (NP_000215) produced in E.coli.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

Synonyms

keratin 18 , CK-18 , CYK18 , K18

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