Cytokeratin 8 antibody [N1C1],Genetex,GTX112975

Host

Rabbit

Reactivity

Human, Mouse, Rat, Zebrafish

Application

WB ICC/IF IHC-P

Conjugate

Unconjugated

Platform ID

BAB317327134

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameCytokeratin 8 antibody [N1C1]
Cat. No.GTX112975
Gene ID (Entrez)3856
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat, Zebrafish
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P
ClonalityPolyclonal
Concentration0.12 mg/ml (Please refer to the vial label for the specific concentration.)
TargetKRT8
ImmunogenRecombinant protein encompassing a sequence within the center region of human Cytokeratin 8. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 1% BSA, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq]

Synonyms

keratin 8 , CARD2 , CK-8 , CK8 , CYK8 , K2C8 , K8 , KO

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