Cytokeratin AE3 Rabbit pAb- ABclonal,ABclonal,A26789

Reactivity

Human

Application

WB, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB207578459

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameCytokeratin AE3 Rabbit pAb- ABclonal
Cat. No.A26789
RRID#N/A
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IHC-P, ELISA
Working DilutionsWB:1:3000 - 1:18000 | IHC-P:1:500 - 1:2000 | ELISA:Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight28-60kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

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