DGCR8 Rabbit pAb- ABclonal,ABclonal,A18630

Reactivity

Human, Mouse, Rat

Application

WB, IHC-P, IP, ELISA

Platform ID

BAB251068838

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

NameDGCR8 Rabbit pAb- ABclonal
Cat. No.A18630
RRID#N/A
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationWB, IHC-P, IP, ELISA
Working DilutionsWB:1:500 - 1:2000 | IHC-P:1:50 - 1:200 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight110kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.

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