DNA Ligase III/LIG3 Rabbit mAb,ABclonal,A22136

Reactivity

Human,Mouse,Rat

Application

WB, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB851992900

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameDNA Ligase III/LIG3 Rabbit mAb
Cat. No.A22136
Accession NumberP49916
Gene ID (Entrez)3980
IsotypeIgG
ReactivityHuman,Mouse,Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, ELISA
Working DilutionsWB:1:1000 - 1:5000 | IHC-P:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC55533
Molecular Weight96kDa(DNA Ligase III β); 103kDa(DNA Ligase III α)
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms

LIG2; MTDPS20; LIG3alpha; DNA Ligase III/LIG3

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