DNA Ligase IV Recombinant Antibody,Bioss,bsm-54131r

Host

Rabbit

Reactivity

Human

Application

WB, IHC-P, IHC-F, IF, ICC/IF

Conjugate

Unconjugated

Platform ID

BAB042388822

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameDNA Ligase IV Recombinant Antibody
Cat. No.bsm-54131r
Accession NumberP49917
Gene ID (Entrez)3981
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IF, ICC/IF
Working DilutionsWB:1:300-5000 | IHC-P:1:200-400 | IHC-F:1:100-500 | IF: | ICC/IF:1:50-100
ClonalityRecombinant
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Synonyms

DNA ligase 4; DNA ligase IV; Polydeoxyribonucleotide synthase [ATP] 4; LIG4.

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.