DNA Methyltransferase 3 Alpha (DNMT3A) Antibody,Abbexa,abx002272

DNMT3A Antibody is a Rabbit Polyclonal antibody against DNMT3A. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.