DNA-PKcs (phospho Thr2609) antibody,Genetex,GTX24194
Host
Rabbit
Reactivity
Human
Application
WB ICC/IF IP ELISA
Conjugate
Unconjugated
Platform ID
BAB052797847
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
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Product Specifications
Scientific Background
Synonyms
Specifications
NameDNA-PKcs (phospho Thr2609) antibody
Cat. No.GTX24194
Gene ID (Entrez)5591
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF IP ELISA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetPRKDC
ImmunogenSynthetic peptide corresponding to amino acids surrounding Thr 2609 of human DNA PKcs.
PurityPurified by antigen-affinity chromatography.From serum
Appearance/FormLiquid
Formulation20mM Potassium Phosphate, 150mM NaCl,0.01% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only
Scientific Background
DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer.
Synonyms
protein kinase, DNA-activated, catalytic subunit , DNA-PKC , DNA-PKcs , DNAPK , DNAPKc , DNPK1 , HYRC , HYRC1 , IMD26 , XRCC7 , p350
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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