DNA ligase III antibody [1F3],Genetex,GTX70143

Host

Mouse

Reactivity

Human, Mouse, Chicken

Application

WB ICC/IF IP Blocking PLA

Conjugate

Unconjugated

Platform ID

BAB421865667

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameDNA ligase III antibody [1F3]
Cat. No.GTX70143
Gene ID (Entrez)3980
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Chicken
ConjugationUnconjugated
ApplicationWB ICC/IF IP Blocking PLA
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetLIG3
ImmunogenRecombinant full-length human DNA Ligase III-b.
PurityProtein G affinity purified.From hybridoma culture supernatant.
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Synonyms

DNA ligase 3 , LIG2 , LIG3alpha

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