DNMT3B antibody,Genetex,GTX00735

Host

Rabbit

Reactivity

Mouse

Application

WB ICC/IF IHC-Fr IHC-Wm IP ChIP assay

Conjugate

Unconjugated

Platform ID

BAB776696646

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameDNMT3B antibody
Cat. No.GTX00735
Gene ID (Entrez)13436
HostRabbit
IsotypeIgG
ReactivityMouse
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-Fr IHC-Wm IP ChIP assay
ClonalityPolyclonal
Concentration~0.3 mg/ml (Please refer to the vial label for the specific concentration.)
TargetDnmt3b
ImmunogenRecombinant mouse Dnmt3b (amino acids 1-181)
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS, 50% Glycerol,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Loss of function of this gene results in severe developmental defects and loss of viability. Mutation of the related gene in humans causes immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. There is a pseudogene for this gene located adjacent to this gene in the same region of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Nov 2012]

Synonyms

DNA methyltransferase 3B , MmuIIIB

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