DR4 antibody [DR-4-02] (PE),Genetex,GTX80184

Host

Mouse

Reactivity

Human

Application

FCM

Conjugate

Phycoerythrin (PE) Wavelength

Platform ID

BAB060271729

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameDR4 antibody [DR-4-02] (PE)
Cat. No.GTX80184
Gene ID (Entrez)8797
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationPhycoerythrin (PE) Wavelength
ApplicationFCM
ClonalityMonoclonal
Concentration0.1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTNFRSF10A
ImmunogenFusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1.
PurityPurified by size-exclusion chromatography
Appearance/FormLiquid
FormulationPBS,15mM Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]

Synonyms

APO2 , CD261 , DR4 , TNF receptor superfamily member 10a , TNFRSF10A , TRAILR1 , TRAIL-R1

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