DYNC1LI1 antibody [1B9],Genetex,GTX84596

Host

Mouse

Reactivity

Human, Mouse, Dog, Monkey

Application

WB ICC/IF FCM

Conjugate

Unconjugated

Platform ID

BAB321491341

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameDYNC1LI1 antibody [1B9]
Cat. No.GTX84596
Gene ID (Entrez)51143
HostMouse
IsotypeIgG2b
ReactivityHuman, Mouse, Dog, Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF FCM
ClonalityMonoclonal
Concentration0.93 mg/ml (Please refer to the vial label for the specific concentration.)
TargetDYNC1LI1
ImmunogenFull length human recombinant protein of human DYNC1LI1 (NP_057225) produced in HEK293T cell.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

Synonyms

dynein cytoplasmic 1 light intermediate chain 1 , DLC-A , DNCLI1 , LIC1

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