DcR1 antibody,Genetex,GTX25975

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF ELISA

Conjugate

Unconjugated

Platform ID

BAB179459549

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameDcR1 antibody
Cat. No.GTX25975
Gene ID (Entrez)8794
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF ELISA
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetTNFRSF10C
ImmunogenPeptide corresponding to aa 149- 167 at the extracellular domain (ED) of human DcR1 precursor (accession no. AF012536).
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

Synonyms

CD263 , DCR1 , DCR1TNFR , LIT , TNF receptor superfamily member 10c , TNFRSF10C , TRAILR3 , TRID , DcR1 , TRAIL-R3

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