DcR1 antibody [TRAIL-R3-02] (Azide Free),Genetex,GTX79877

Host

Mouse

Reactivity

Human

Application

FCM

Conjugate

Unconjugated

Platform ID

BAB558922377

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameDcR1 antibody [TRAIL-R3-02] (Azide Free)
Cat. No.GTX79877
Gene ID (Entrez)8794
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationFCM
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTNFRSF10C
ImmunogenTRAIL-R3 (aa 1-280) - hIgGhc fusion protein
PurityProtein A purified
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

Synonyms

CD263 , DCR1 , DCR1TNFR , LIT , TNF receptor superfamily member 10c , TNFRSF10C , TRAILR3 , TRID , DcR1 , TRAIL-R3

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