DcR2 Antibody (YA2588),MedChemexpress,HY-P82843

DcR2 Antibody (YA2588) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DcR2.

Host

Rabbit

Reactivity

Human

Application

WB,IHC-P,ICC/IF

Conjugate

Non-conjugated

Platform ID

BAB203729504

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
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MedChemexpress

Master of Bioactive Molecules

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Email:

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Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameDcR2 Antibody (YA2588)
Cat. No.HY-P82843
Accession NumberQ9UBN6
Gene ID (Entrez)8793
HostRabbit
RRIDAB_3104936
IsotypeIgG
SensitivityEndogenous
ReactivityHuman
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF
Working DilutionsWB: 1:500-1:1000; IHC-P: 1:50-1:100; ICC/IF: 1:50-1:200
ClonalityRecombinant,Monoclonal
Clone NumberYA2588
Molecular WeightPredicted band size: 42 kDa; Observed band size: 36 kDa
ImmunogenA synthesized peptide derived from human DCR2 aa350-386.
PurityAffinity Purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

DcR2 is a receptor for the cytotoxic ligand TRAIL, featuring a truncated death domain that prevents it from inducing apoptosis but enables protection against TRAIL-mediated apoptosis. Its ability to induce the NF-kappa-B pathway is contradictory: some studies report it cannot, while others indicate it can.

Synonyms

TNFRSF10D; DCR2; TRAILR4; TRUNDD; Tumor necrosis factor receptor superfamily member 10D; Decoy receptor 2; DcR2; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4; TRAIL-R4; TRAIL receptor with a truncated death domain; CD

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