Denosumab Biosimilar - Research Grade,ichor.bio,ICH4019

Detects human RANK Ligand. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Denosumab.

Host

Humanized

Reactivity

Human

Platform ID

BAB135389218

ichor.bio

Headquarters

Grove Business Park Downsview Road Wantage OX12 9FF

Contact

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Product Specifications
Scientific Background
Synonyms

Specifications

NameDenosumab Biosimilar - Research Grade
Cat. No.ICH4019
Accession NumberO14788
HostHumanized
IsotypeHuman IgG2
ReactivityHuman
Concentration1.0 - 5.0 mg/ml
TargetRANKL
Purity>95% by SDS-PAGE and HPLC
Endotoxin Level≤ 1.0 EU/mg as determined by the LAL method
ShippingBlue ice
FormulationICH3001-100ml ICH3002-100ml ICH3003-100ml
StorageStable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Regulatory StatusFor research use only

Scientific Background

Denosumab biosimilar is a human IgG2 monoclonal antibody that binds to human RANKL. Denosumab has an approximate molecular weight of 147 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells.

Synonyms

Tumor necrosis factor ligand superfamily member 11, Tnfsf11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TRANCE, CD254, Rank Ligang

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