Desmoglein 1 antibody [DSG1/1733],Genetex,GTX34675

Host

Mouse

Reactivity

Human

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB515654420

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameDesmoglein 1 antibody [DSG1/1733]
Cat. No.GTX34675
Gene ID (Entrez)1828
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P
ClonalityMonoclonal
Concentration0.2 mg/ml (Please refer to the vial label for the specific concentration.)
TargetDSG1
ImmunogenRecombinant human desmoglein-1 protein fragment corresponding to intracellular domain
PurityProtein A/G purified
Appearance/FormLiquid
FormulationPBS, 0.05% BSA,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]

Synonyms

CDHF4 , DG1 , DSG , DSG1 , EPKHE , EPKHIA , PPKS1 , SPPK1 , desmoglein 1 , Desmoglein 1

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