DiMethyl-Histone H3-K79 Rabbit mAb- ABclonal,ABclonal,A22086

Reactivity

Human, Mouse, Rat, Other (Wide Range Predicted)

Application

WB, IP, IF/ICC, IF-P, IHC-P, DB, ChIP, ChIP-seq, ELISA

Conjugate

Unconjugated

Platform ID

BAB156702891

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

Tel:
Fax:

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameDiMethyl-Histone H3-K79 Rabbit mAb- ABclonal
Cat. No.A22086
Accession NumberQ16695
Gene ID (Entrez)8290
IsotypeIgG
ReactivityHuman, Mouse, Rat, Other (Wide Range Predicted)
ConjugationUnconjugated
ApplicationWB, IP, IF/ICC, IF-P, IHC-P, DB, ChIP, ChIP-seq, ELISA
Working DilutionsWB:1:30000 - 1:120000 | IP:0.5μg-4μg antibody for 200μg-400μg extracts of whole cells | IF/ICC:1:200 - 1:400 | IF-P:1:50 - 1:200 | IHC-P:1:2000 - 1:10000 | DB:1:2000 - 1:20000 | ChIP:5μg antibody for 5μg-10μg of Chromatin | ChIP-seq:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC54084
Molecular Weight17 kDa
ImmunogenA synthetic dimethylated peptide around K79 of human Histone H3-K79 (NP_003520.1).
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Synonyms

H3t; H3.4; H3/g; H3FT; H3C16; HIST3H3; DiMethyl-Histone H3-K79

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.