Diablo antibody [78-1-118],Genetex,GTX30249

Host

Mouse

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF IP

Conjugate

Unconjugated

Platform ID

BAB435481657

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameDiablo antibody [78-1-118]
Cat. No.GTX30249
Gene ID (Entrez)56616
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IP
ClonalityMonoclonal
TargetDIABLO
ImmunogenRecombinant mature human Smac (lacks amino acids 1-55 present in Smac precursor). [UniProt# Q9NR28]
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. [provided by RefSeq]

Synonyms

diablo IAP-binding mitochondrial protein , DFNA64 , SMAC

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