Diablo antibody [AT19F2],Genetex,GTX57593

Host

Mouse

Reactivity

Human

Application

WB ICC/IF FCM

Conjugate

Unconjugated

Platform ID

BAB763569157

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameDiablo antibody [AT19F2]
Cat. No.GTX57593
Gene ID (Entrez)56616
HostMouse
IsotypeIgG2a
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF FCM
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetDIABLO
ImmunogenThe clone AT19F2 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SMAC/Diablo protein.
PurityProtein A Purified
Appearance/FormLiquid
FormulationPBS, 10% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

Synonyms

diablo IAP-binding mitochondrial protein , DFNA64 , DIABLO , SMAC , diablo IAPbinding mitochondrial protein , Smac , Diablo

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